Manuka Honey Helping with Gut Health

Good health starts with the belly yes, really.
 Gut Health refers to the balance of microorganisms that live in the digestive tract. Without proper care for gut, digestive disorders like heartburn, irritable bowel syndrome (IBS) and gastroesophageal reflux diseases (GERD) can occcur. It is always better to make better gut health choices today because it is a vital function for physical and mental health, immunity, and more.
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Reduced Stress
Practice meditation, deep breathing exercises, and progressive muscle relaxation. 

Exercising regularly, sleeping well and eating healthful diet can also reduce stress levels.
Get sufficient sleep
Routinely sleeping less than six or seven hours a night demolishes your immune system more than doubling your risk of cancer . - Matthew Walker, Why We Sleep: Unlocking the power of Sleep and Dreams 
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Lack of sleep can increase stress levels causing leaky gut- where toxins are able to breakthrough into the bloodstream.

Getting enough good-quality sleep can improve mood, cognition, and gut health.
Chew your food 
Food has to be adequality broken down for the digestive enzymes to act on it before it enters the intestine.

A common piece of advice is to chew your food an estimated 32 times before swallowing.

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Take Comvita Manuka Honey
Comvita UMF™ Manuka Honey's 
anti-inflammatory and prebiotic bioactivities are proven to reduce inflammation and maintain a healthy digestive system.

Take a spoonful of Manuka Honey every morning to ensure that your gut is always working as it should!

Benefits of Manuka Honey and How it Helps With Gut Health

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               Prebiotic Effects

Manuka honey, a wound treatment used to eradicate bacteria, resolve inflammation, and promote wound healing, is a current focus in the tissue engineering community as a tissue template additive. 

However, Manuka honey’s effect on neutrophils during the inflammation-resolving phase has yet to be examined. This study investigates the effect of 0.5% and 3% Manuka honey on the release of cytokines, chemokines, and matrix-degrading enzymes from a dHL-60 neutrophil model in the presence of anti-inflammatory stimuli (TGF-β, IL-4, IL-4 +IL-13). 

We hypothesized that Manuka honey would reduce the output of pro-inflammatory signals and increase the release of anti-inflammatory signals. The results of this study indicate that 0.5% honey significantly increases the release of CXCL8/IL-8, CCL2/MCP-1, CCL4/MIP-1β, CCL20/MIP-3α, IL-4, IL-1ra, and FGF-13 while reducing Proteinase 3 release in the anti-inflammatory-stimulated models. However, 3% honey significantly increased the release of TNF-α and CXCL8/IL-8 while reducing the release of all other analytes.

 We replicated a subset of the most notable findings in primary human neutrophils, and the consistent results indicate that the HL-60 data are relevant to the performance of primary cells. 

These findings demonstrate the variable effects of Manuka honey on the release of cytokines, chemokines, and matrix-degrading enzymes of this model of neutrophil anti-inflammatory activity. 

This study reinforces the importance of tailoring the concentration of Manuka honey in a wound or tissue template to elicit the desired effects during the inflammation-resolving phase of wound healing. 

Future in vivo investigation should be undertaken to translate these results to a physiologically-relevant wound environment.  

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Strengthen Immune System
Sooth Sore Throat
Double Protection
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Strong Antibacterial  Properties
Honey has been used as a medicine throughout the history of the human race. One of the most common and persistent therapeutic uses of honey has been as a wound dressing, almost certainly due to its antimicrobial properties. With the advent of highly active antibiotics in the 1960s, honey was dismissed as a “worthless but harmless substance” (). However, the current and growing crisis of antibiotic resistance has revived interest in the use of honey, both as an effective agent in its own right and as a therapeutic lead to develop new methods of treatment. Honey is usually derived from the nectar of flowers and produced by bees, most commonly the European honey bee Apis mellifera, and is a complex mix of sugars, amino acids, phenolics, and other substances. Honey types derived from different flowering plants vary substantially in their ability to kill bacteria, and this has complicated the literature on honey and made it sometimes difficult to reproduce results across different studies (). The majority of recent studies investigating the mechanism of action of honey have focused on well-characterized, standardized active manuka honey produced by certain Leptospermum species native to New Zealand and Australia, which has been registered as a wound care product with appropriate medical regulatory bodies. Thus, unless otherwise specified, this review will focus on manuka honey.
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